Production:
 
Morphine Hydrochloride 1,0g (one gram)
Dissolve in Glandomed®      500ml
Ad hydrochloric acid 10%     2,0ml  for pH adjustment
 


Analysis:
The pH of the ready to use solution is about 6.5 to 7.0
The examination of the pH value with the indicator paper MERCK (pH 1-10) is sufficient exact.
 
Stability
was examined by Klaus Schmelzer by means of HPLC. The stability after 4 weeks storage at room temperaure is approximatitly 98-99%. It is recommended to use the solution within four weeks after preparation.
 


Application:

This solution is used in case of strong and strongest mouth pain or sores.
 
For rinsing 15 ml of the solution (=30mg morphine hydrochloride) can be taken 4 times a day. Keep the solution 2 minutes in your mouth and then spit it out. Do not drink it.
For toxic reasons the bottles are to be provided with a child-safe catch.
 
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Customers information:
 
Glandomed® - Morphine 0,2%
 
 
HPLC-protocol
 
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