Pathophysiology, risk factors and scoring oral mucositis

Mucositis develops under chemo- and radiotherapy due to reactive oxygen radicals energizing cascade-like reaction sequences which produce cell factors that destroy the own cells of the body in addition to the cancerous cells. At first inflammation of the epithelium occurs. If it continues ulcers will develop. More and more bacteria, fungi and viruses settle in the mucous lining. Patient will suffer from severe mouth pain. As a result, it is no longer possible to take up food via the oral route. The quality of life diminishes and the patient is at high risk for infections. 
The risk for a mucositis depends on the type of cancer treatment, the general health of the patient, the oral hygiene and the strict observance of recognized prophylaxis or instructions for therapy.
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